Related Experiment Video
Updated: Aug 5, 2026

Detection of Infectious Virus from Field-collected Mosquitoes by Vero Cell Culture Assay
Published on: June 9, 2011
[Fever of unknown origin]
S Fronhoffs1, D Bokemeyer, F J Heidgen
1Medizinische Universitätspoliklinik Bonn.
Abstract:
A 25-year-old patient presented with fever over a period of more than three months, night sweats, fatigue and a weight loss of more than 10 kg. A splenomegaly and an enlargement of cervical, thoracic and abdominal lymph nodes were found. The suspected malignant hematologic disorder could not be confirmed. Instead, epithelioid noncaseating granulomas in the bone marrow and a cervical lymph node as well as an elevated serum ACE and a lymphocytic alveolitis were found. These findings led us to the conclusion that the patient was suffering from sarcoidosis. Treatment with corticosteroids resulted in complete regression of all symptoms, including the splenomegaly and the enlargement of the lymph nodes. Sarcoidosis is an important consideration in differential diagnosis of fever of unknown origin, even in the absence of pathological changes on X-ray films of the chest.
More Related Videos
Related Concept Videos
Increased Body Temperature
Methods of reducing fever
Pharmacological Methods of Reducing Fever:
Types of Fever
Here are the different types of fever:
Patterns of Fever
Rocky Mountain Spotted Fever
Yellow Fever

