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The Multiple Sclerosis Performance Test (MSPT): An iPad-Based Disability Assessment Tool
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[Function of acoustic analyzer in multiple sclerosis in exacerbation]

A M Ryndina, I M Barbas, N V Mal'tseva

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    Multiple sclerosis (MS) patients frequently experience auditory system dysfunction, particularly in the brain stem. While detoxication therapy shows neurological improvement, auditory deficits may persist, indicating potential prognostic value.

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    Area of Science:

    • Neuroscience
    • Audiology
    • Otolaryngology

    Context:

    • Aggravated multiple sclerosis (MS) presents complex neurological challenges.
    • Auditory system involvement in MS is often underdiagnosed.
    • Comprehensive audiological assessment is crucial for MS patients.

    Purpose:

    • To investigate the prevalence and characteristics of auditory system dysfunction in patients with aggravated multiple sclerosis.
    • To evaluate the impact of sorption detoxication therapy on auditory function in MS patients.
    • To explore the relationship between subjective/neurological improvements and objective acoustic criteria post-therapy.

    Summary:

    • Audiometric examinations, including pure-tone, speech, and evoked potentials, were performed on 51 aggravated MS patients.
    • Acoustic analyzer dysfunction, especially sound laterality, was found in a significant percentage of patients (42-83%).
    • Hearing impairment predominantly affected the brain stem (68%), with occasional cochlear involvement (15%).
    • Sorption detoxication therapy yielded subjective and neurological improvements in 100% of patients, but only 59% showed acoustic improvement.
    • The discrepancy between subjective and acoustic responses suggests subclinical auditory symptoms with potential prognostic implications.

    Impact:

    • Highlights the high incidence of auditory pathway dysfunction in MS, often subclinical.
    • Suggests that persistent auditory deficits post-therapy may serve as a prognostic indicator in MS.
    • Emphasizes the need for routine audiological evaluations in the management of multiple sclerosis.