Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Fatal zipeprol intoxication

P Kintz1, V Cirimele, A Tracqui

  • 1Institut de Médecine Légale, Strasbourg, France.

International Journal of Legal Medicine
|January 1, 1995
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A deadly root and the science behind it: LC-HRMS and LC-MS/MS analysis in an aconite-induced suicide.

Forensic toxicology·2025
Same author

Semaglutide and health risk: Development and validation of a LC-HRMS method for testing semaglutide in whole blood and application to real cases.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences·2024
Same author

Bariatric surgery and changes in metformin distribution: About a fatal case.

Journal of pharmaceutical and biomedical analysis·2024
Same author

[Testing for cannabis and synthetic cannabinoids in human specimens].

Bulletin de l'Academie nationale de medecine·2020
Same author

First identification of a diuretic, hydrochlorothiazide, in hair: Application to a doping case and interpretation of the results.

Drug testing and analysis·2018
Same author

European guidelines for workplace drug and alcohol testing in hair.

Drug testing and analysis·2016
Same journal

Deep Learning-Based Panoramic Radiograph Retrieval from Antemortem Images for Forensic Identification.

International journal of legal medicine·2026
Same journal

Forensic age estimation using knee MRI: application of the Vieth staging system in a French population.

International journal of legal medicine·2026
Same journal

A swab and wetting agent combination investigation for enhanced touch DNA recovery: A step towards standardisation.

International journal of legal medicine·2026
Same journal

Paternal lineage diversity in the Sikh males of Sri Ganganagar, Rajasthan through 27 Y-STRs.

International journal of legal medicine·2026
Same journal

Testing the accuracy of Cameriere's original and European formulae radiographic method of dental age estimation.

International journal of legal medicine·2026
Same journal

Machine learning algorithms in the estimation of sex from 3DCT-generated cranial and pelvic measurements.

International journal of legal medicine·2026
See all related articles

A zipeprol overdose caused a fatality, confirmed by drug quantification in biological samples. Chronic zipeprol abuse was evident through hair analysis, indicating long-term substance misuse.

Area of Science:

  • Forensic Toxicology
  • Analytical Chemistry

Background:

  • Zipeprol is an antitussive medication with potential for abuse.
  • Fatalities associated with zipeprol are rare, necessitating detailed toxicological investigation.

Observation:

  • A case of zipeprol ingestion leading to a fatal outcome is presented.
  • Biological samples (blood and hair) were collected for drug analysis.

Findings:

  • Capillary gas chromatography-mass spectrometry quantified zipeprol in biological matrices.
  • Femoral blood zipeprol concentration was 2.85 mg/L.
  • Hair analysis revealed a zipeprol concentration of 7.34 ng/mg, indicative of chronic abuse.

Implications:

  • This case highlights the lethal potential of zipeprol, even at seemingly moderate concentrations.

Related Experiment Videos

  • Toxicological analysis of blood and hair is crucial for determining drug exposure and abuse patterns.
  • Findings contribute to the understanding of zipeprol pharmacokinetics and toxicity in fatal cases.