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Endogenous histamine induces c-fos expression within paraventricular and supraoptic nuclei
M L Vizuete1, V Dimitriadou, E Traiffort
1Laboratoire de Physiologie, Faculté de Pharmacie, Université René Descartes, Paris, France.
Neuroreport
|May 9, 1995
Abstract:
Thioperamide, an H3-receptor antagonist that enhances endogenous histamine release, induced c-fos mRNA expression and Fos-like immunoreactivity in magnocellular neurones of rat supraoptic and paraventricular nuclei. This response was prevented as a result of blockade of the H1 receptor, indicating that endogenous histamine is able to activate these magnocellular neurones via stimulation of this receptor.