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Related Experiment Videos

Gold-tip laser sleeve for a bare fiber

A P Perlmutter1, J N Macaluso

  • 1Department of Urology, James Buchanan Brady Foundation, New York Hospital-Cornell Medical Center, NY, USA.

Journal of Endourology
|April 1, 1995
PubMed
Summary

A gold-tip laser sleeve effectively delivered Neodymium-doped Yttrium Aluminum Garnet (Nd:YAG) laser irradiation to the prostate in canine and human studies. Higher wattage correlated with increased intraprostatic temperatures, demonstrating a promising minimally invasive treatment approach.

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Area of Science:

  • Urology
  • Medical Devices
  • Laser Therapy

Background:

  • Prostate conditions require effective and minimally invasive treatment options.
  • Nd:YAG laser therapy offers a potential thermal ablation method.
  • Developing precise delivery systems for laser energy is crucial for targeted treatment.

Purpose of the Study:

  • To evaluate the efficacy and safety of a gold-tip laser sleeve for Nd:YAG laser prostate irradiation.
  • To assess intraprostatic heating profiles and the impact of varying energy levels.
  • To report preliminary clinical outcomes in a pilot patient series.

Main Methods:

  • Utilized a gold-tip laser sleeve with a bare laser fiber for Nd:YAG laser irradiation.
  • Conducted studies in a canine model via suprapubic cystotomy and a pilot clinical series.

Related Experiment Videos

  • Monitored procedures with video endoscopy and measured intraprostatic temperatures using interstitial thermometry.
  • Investigated the effect of the "popcorn effect" on thermal conduction.

    • Main Results:

    • Higher laser wattage led to increased intraprostatic temperatures, provided carbonization was avoided.
    • The "popcorn effect" caused superficial temperature decreases but did not impede deeper thermal conduction.
    • The Ablaser catheter facilitated controlled energy delivery in the animal model.
    • Preliminary clinical treatment yielded positive patient outcomes.

    Conclusions:

    • The gold-tip laser sleeve is a viable tool for Nd:YAG laser prostate irradiation.
    • Precise temperature control is achievable, with wattage influencing heating depth.
    • The "popcorn effect" is a manageable phenomenon during laser prostatectomy.
    • Initial clinical results suggest this method is effective for treating prostate conditions.