Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Neurotransmitters regulating feline aggressive behavior

A Siegel1, K Schubert

  • 1Department of Neurosciences, New Jersey Medical School, Newark 07103-2714, USA.

Reviews in the Neurosciences
|January 1, 1995
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

FKRP-dependent glycosylation of fibronectin regulates muscle pathology in muscular dystrophy.

Nature communications·2021
Same author

Fluoroscopic-guided laparoscopic ileocolic resection with retrieval of retained (PillCam<sup>®</sup>) wireless capsule endoscope.

Techniques in coloproctology·2019
Same author

Evaluation of a scapula spinal marker cluster to track the scapula kinematics during manual wheelchair propulsion.

Computer methods in biomechanics and biomedical engineering·2017
Same author

Tracking the scapula motion through multibody kinematics optimisation to study manual wheelchair propulsion.

Computer methods in biomechanics and biomedical engineering·2017
Same author

Boolean network identification from perturbation time series data combining dynamics abstraction and logic programming.

Bio Systems·2016
Same author

Plant-virus-based vectors for gene transfer may be of considerable use despite a presumed high error frequency during RNA synthesis.

Plant molecular biology·2013
Same journal

A review of Alzheimer's disease diagnosis and prognosis models based on multimodal deep learning.

Reviews in the neurosciences·2026
Same journal

<i>Helicobacter pylori</i> infection and neurological disorders: association, mechanisms, and clinical implications.

Reviews in the neurosciences·2026
Same journal

Role of Toll-like receptors and oral-gut-brain axis in neurodegenerative and neuropsychiatric disorders.

Reviews in the neurosciences·2026
Same journal

The potential mechanisms of exercise-regulated mechanically sensitive ion channels in promoting spinal cord injury repair: a hypothesis-driven narrative review.

Reviews in the neurosciences·2026
Same journal

Behavioral, neural and neurochemical basis of effort-related decision making.

Reviews in the neurosciences·2026
Same journal

Growth differentiation factor 11 (GDF11) signaling in neural stem cell regulation: molecular and cellular insights.

Reviews in the neurosciences·2026
See all related articles

Neural pathways in cats organize aggressive behaviors, with distinct systems for defensive rage and predatory attacks. Excitatory and inhibitory pathways involving the hypothalamus and amygdala modulate these responses.

Area of Science:

  • Neuroscience
  • Animal Behavior

Background:

  • Aggressive responses in cats are complex, involving distinct behavioral patterns like defensive rage and predatory attacks.
  • Understanding the neural circuitry underlying these behaviors is crucial for comprehending brain function and modulation of aggression.

Purpose of the Study:

  • To review and analyze the distinct neural pathways involved in the expression and modulation of aggressive behaviors in cats.
  • To elucidate the neurochemical mechanisms, including neurotransmitters and receptors, that mediate these aggressive responses.

Main Methods:

  • Review of experimental studies on the neurobiology of aggression in cats.
  • Analysis of neuroanatomical projections from the hypothalamus and amygdala to the periaqueductal gray (PAG).
  • Examination of the roles of specific neurotransmitters (excitatory amino acids, substance P, opioid peptides) and receptors (NMDA, NK1, mu) in modulating aggressive behaviors.

Related Experiment Videos

Main Results:

  • Two distinct pathway sets organize aggressive responses: one for attack behavior (medial and lateral hypothalamus to PAG) and modulatory pathways from the amygdala.
  • Defensive rage is mediated by an excitatory pathway from the medial hypothalamus to the PAG, utilizing NMDA receptors.
  • Facilitatory pathways from the amygdala (basal complex to PAG, medial nucleus to medial hypothalamus) and an inhibitory pathway (central nucleus to PAG) modulate aggression.

Conclusions:

  • The expression and modulation of aggressive behaviors in cats involve intricate neural networks with both excitatory and inhibitory components.
  • Specific pathways and neurochemical systems, including excitatory amino acids, substance P, and opioid peptides, play critical roles in regulating defensive rage and predatory attack behaviors.
  • Further research is needed to fully understand the complex mechanisms governing different forms of aggression.