Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Implants for tremor

D L McLellan1

  • 1University Rehabilitation Research Unit, Southampton General Hospital, UK.

Bailliere'S Clinical Neurology
|April 1, 1995
PubMed
Summary
This summary is machine-generated.

Electrical stimulation of the ventrolateral thalamus nucleus can reduce tremors in Parkinson's disease and essential tremor. This method shows promise with fewer risks than ablation, but requires long-term studies.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Current priorities in the understanding and management of disorders of consciousness.

Neuropsychological rehabilitation·2018
Same author

Renal biopsy in congenital ureteropelvic junction obstruction: evidence for parenchymal maldevelopment.

Kidney international·2005
Same author

A study to evaluate the met and unmet needs of members belonging to Young Stroke groups affiliated with the Stroke Association.

Disability and rehabilitation·2003
Same author

The unmet needs of young people who have had a stroke: results of a national UK survey.

Disability and rehabilitation·2002
Same author

Transferring people safely with manual handling equipment.

Clinical rehabilitation·2002
Same author

The use of leg lifting equipment.

Nursing standard (Royal College of Nursing (Great Britain) : 1987)·2002
Same journal

Remyelination in demyelinating disease.

Bailliere's clinical neurology·1999
Same journal

Other immunomodulatory therapies in multiple sclerosis.

Bailliere's clinical neurology·1999
Same journal

Copolymer-1.

Bailliere's clinical neurology·1999
Same journal

Interferon beta 1a.

Bailliere's clinical neurology·1999
Same journal

Treatment of multiple sclerosis with interferon beta 1b.

Bailliere's clinical neurology·1999
Same journal

The cause and management of bladder, sexual and bowel symptoms in multiple sclerosis.

Bailliere's clinical neurology·1999
See all related articles

Area of Science:

  • Neurology
  • Neurosurgery
  • Medical Engineering

Background:

  • Intention and resting tremors, often seen in Parkinson's disease and essential tremor, significantly impact patient quality of life.
  • Current treatments like stereotactic ablation carry risks of physical or cognitive impairment.

Purpose of the Study:

  • To evaluate the efficacy and safety of chronic or contingent electrical stimulation in the ventrolateral nucleus of the thalamus for tremor suppression.
  • To compare the risk profile of this neuromodulation technique against traditional ablative procedures.

Main Methods:

  • Electrical stimulation was applied chronically or contingently to the ventrolateral nucleus of the thalamus in patients with intention and resting tremors.
  • Patient outcomes were assessed for tremor suppression and adverse physical or cognitive effects.

Related Experiment Videos

Main Results:

  • Electrical stimulation demonstrated the ability to suppress contralateral intention tremor and resting tremor associated with Parkinson's disease and idiopathic tremor.
  • The procedure appears to present a lower risk of physical or cognitive impairment compared to stereotactic ablation.

Conclusions:

  • Electrical stimulation of the ventrolateral thalamus is a potentially safer alternative for managing debilitating tremors.
  • Further long-term follow-up studies are essential to establish the true clinical value and optimal application of this neuromodulation technique.