[Immunostimulation therapy in patients with alopecia areata]

The authors recorded decreased values of active and total E rosettes and increased values of IgM and C3 components of complement in 13 patients with alopecia areata. Direct immunofluorescence examination of skin excisions from the alopetic foci revealed immunocomplexes in hair follicles. On the basis of these examinations, excluding other causes of the disease of alopecia areata, the authors indicated the general immunostimulation therapy. (Decabris tbl., Transfer faktor inj.). This therapy resulted in an increase in active and total E rosettes and a decrease in IgM, and thus in the recovery of cellular and indirectly in the humoral component of immunity in the peripheral blood under the circumstances of a favourable clinical therapeutic effect.