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Published on: September 10, 2018
Concomitant positive patch test results with standard screening tray in North America 1985-1989
D L Holness1, J R Nethercott, R M Adams
1University of Toronto, Canada.
Contact Dermatitis
|May 1, 1995
Summary
Simultaneous patch test reactions are common and can indicate multiple allergies or cross-sensitization. Understanding these concurrent responses is crucial for accurate allergy diagnosis and management.
Area of Science:
- Dermatology
- Allergology
- Immunology
Background:
- Patch testing is a standard diagnostic tool for allergic contact dermatitis.
- Simultaneous reactions to different patch test substances can complicate interpretation.
- Potential causes include concurrent sensitization, cross-sensitization, multiple sensitizations, or the angry back syndrome.
Purpose of the Study:
- To investigate the frequency and implications of simultaneous reactions in patch testing.
- To document associations between specific substances causing concurrent responses.
Main Methods:
- Review of patch test results and patient histories.
- Analysis of cases exhibiting simultaneous positive reactions to multiple allergens.
Main Results:
- Concurrent patch test responses are not uncommon.
- Identified associations include reactions to chemically similar substances (cross-sensitization) and unrelated allergens.
- The 'angry back syndrome' can also influence simultaneous reactions.
Conclusions:
- Simultaneous patch test reactions have multiple potential causes.
- These findings highlight the complexity of interpreting patch test results.
- Further documentation of these associations is valuable for clinical practice.
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