Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Mortality associated with multiple gestation in Malawi

J M McDermott¹, R Steketee, J Wirima

¹Division of Parasitic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA.

International Journal of Epidemiology

|April 1, 1995

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Bubbles and Dust: Experimental Results of Dissolution Rates of Metal Salts and Glasses From Volcanic Ash Deposits in Terms of Surface Area, Chemistry, and Human Health Impacts.

GeoHealth·2020

Same author

Sulfur mass-independent fractionation in subsurface fracture waters indicates a long-standing sulfur cycle in Precambrian rocks.

Nature communications·2016

Same author

Identification of apple cultivars using RAPD markers.

TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·2013

Same author

Diverse styles of submarine venting on the ultraslow spreading Mid-Cayman Rise.

Proceedings of the National Academy of Sciences of the United States of America·2010

Same author

High Genetic Similarity Among Populations of Phaeosphaeria nodorum Across Wheat Cultivars and Regions in Switzerland.

Phytopathology·2008

Same author

Does inadequate prenatal care contribute to growth retardation among second-born African-American babies?

American journal of epidemiology·1999

Same journal

Dental amalgam, chronic disease risk, and removing mercury from dental practice.

International journal of epidemiology·2026

Same journal

Age at menarche and adverse pregnancy and perinatal outcomes: triangulating evidence from multivariable and Mendelian randomization analyses.

International journal of epidemiology·2026

Same journal

Life-course trajectories of cardiovascular disease risk factors in rural India: Andhra Pradesh Children and Parents Study (APCAPS) 2003-2023.

International journal of epidemiology·2026

Same journal

Cohort Profile Update: The Young Lives study.

International journal of epidemiology·2026

Same journal

From the departing Editors in Chief.

International journal of epidemiology·2026

Same journal

Data Resource Profile: Cheeloo Lifespan Electronic-health reseArch Data-library (Cheeloo LEAD).

International journal of epidemiology·2026

See all related articles

Multiple gestation significantly increases maternal and perinatal mortality in Malawi, primarily due to low birthweight and higher perinatal death rates. The risk did not extend beyond the perinatal period.

Area of Science:

Obstetrics and Gynecology
Global Health
Perinatal Epidemiology

Background:

Multiple gestation is linked to higher maternal, perinatal, and infant mortality rates globally.
Prevalence of multiple gestation is highest in African populations, with limited data from sub-Saharan Africa.

Purpose of the Study:

To estimate the prevalence of multiple gestation in rural Malawi.
To quantify the mortality risks associated with multiple gestation compared to singleton gestations in this region.

Main Methods:

Utilized data from a 1987-1990 prospective study on malaria chemoprophylaxis in pregnant women.
Analyzed birthweight and infant mortality data to assess outcomes of multiple versus singleton gestations.

Main Results:

Keywords:

Africa Africa South Of The Sahara Biology Birth Weight Body Weight Correlation Studies Demographic Factors Developing Countries Eastern Africa English Speaking Africa Infant Mortality Malawi Maternal Mortality Mortality Multiple Birth Physiology Population Population Characteristics Population Dynamics Prospective Studies Reproduction Research Methodology Rural Population Statistical Studies Studies

Related Experiment Videos

Identified 88 (2.2%) multiple gestations among 4049 women.
Mothers with multiple gestations had significantly lower infant survival rates to 1 year (38%) compared to singleton gestations (74%).
Multiple gestation contributed to 5.5% of perinatal, 1.2% of postperinatal, and 11.5% of maternal deaths.

Conclusions:

Multiple gestation in Malawi is associated with increased perinatal and maternal mortality.
The elevated mortality risk was attributed to higher rates of low birthweight and perinatal deaths.
No increased mortality risk was observed after the perinatal period for infants from multiple gestations.