Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Minocycline-induced hyperpigmentation

P H Hung1, J B Caldwell, W D James

  • 1Pentagon Army Health Clinic, Washington, DC, USA.

The Journal of Family Practice
|August 1, 1995
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Clinical Lessons in Dermatology: Insights into Diagnosis, Management, and Professional Practice.

Actas dermo-sifiliograficas·2025
Same author

Simulation and experimental study of a K-band extended interaction oscillator for microwave processing systems.

The Review of scientific instruments·2022
Same author

High performance and high power circularly polarized horn antenna for K-band microwave processing systems.

The Review of scientific instruments·2019
Same author

Safety and effectiveness of amoxicillin in the treatment of inflammatory acne.

International journal of women's dermatology·2018
Same author

Acute and recurrent facial pustulosis: a unique clinical entity?

Journal of the European Academy of Dermatology and Venereology : JEADV·2017
Same author

Spironolactone for the treatment of acne in women, a retrospective study of 110 patients.

International journal of women's dermatology·2017

Minocycline therapy can cause skin and nail hyperpigmentation, a rare side effect. While often reversible, permanent tooth discoloration may occur after long-term minocycline use for acne rosacea.

Area of Science:

  • Dermatology
  • Pharmacology

Background:

  • Minocycline is a commonly prescribed antibiotic for acne vulgaris and rosacea.
  • Hyperpigmentation is an uncommon but recognized side effect of minocycline therapy.

Observation:

  • A 70-year-old male patient presented with hyperpigmentation affecting forearms, hands, nails, sclerae, ears, and teeth.
  • This occurred after 9 years of continuous minocycline treatment for acne rosacea.

Findings:

  • Minocycline-induced hyperpigmentation is not typically dose-dependent.
  • The condition usually resolves after discontinuing minocycline, though tooth discoloration may be permanent.

Implications:

  • Clinicians should be aware of the potential for minocycline-induced hyperpigmentation.

Related Experiment Videos

  • Patient counseling regarding the risk of permanent tooth discoloration is crucial for long-term therapy.