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Use of Ultra-high Field MRI in Small Rodent Models of Polycystic Kidney Disease for In Vivo Phenotyping and Drug Monitoring
Published on: June 23, 2015
Aggressive respiratory support and unilateral nephrectomy for infants with severe perinatal autosomal recessive
S A Bean1, F J Bednarek, W A Primack
1Division of Neonatology, Medical Center of Central Massachusetts, USA.
Abstract:
Newborn infants with severe autosomal recessive polycystic kidney disease often receive minimal intervention because poor respiratory and renal outcomes are anticipated. We describe two patients whose respiratory failure was successfully treated with aggressive intervention. Massive kidneys restricted gastrointestinal capacity and limited feedings. Uninephrectomy allowed adequate enteral feedings and preserved sufficient renal function for homeostasis and growth.
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