Subretinal neovascularization in children and adolescents
E B Goshorn1, D L Hoover, A W Eller
1Department of Ophthalmology, Children's Hospital Pittsburgh, PA, USA.
Summary
Pediatric subretinal neovascular membranes (SRNVM) are rare but often linked to inflammation. A hyperpigmented ring on angiography may indicate spontaneous involution and better visual outcomes in children.
Area of Science:
- Ophthalmology
- Pediatric Ophthalmology
- Retinal Diseases
Background:
- Subretinal neovascular membranes (SRNVM) are uncommon in pediatric patients.
- Understanding the characteristics and prognosis of pediatric SRNVM is crucial for effective management.
Purpose of the Study:
- To retrospectively analyze the clinical presentation, etiology, course, and management of SRNVM in children.
- To identify factors associated with spontaneous involution and visual prognosis in pediatric SRNVM.
Main Methods:
- Retrospective review of 25 pediatric patients (27 eyes) diagnosed with SRNVM.
- Analysis of clinical data, including etiology, treatment, and visual acuity outcomes.
- Fluorescein angiography findings, specifically the presence of a hyperpigmented ring, were evaluated.
Main Results:
- Inflammatory or infectious conditions were the predominant causes of SRNVM in this cohort (10 of 25).
- Of 19 untreated SRNVM, 11 (58%) showed spontaneous involution.
- Nine of the 11 eyes with spontaneous involution achieved a final visual acuity of 20/50 or better.
- A hyperpigmented ring on fluorescein angiography was observed in 9 of the 11 involuted SRNVM.
Conclusions:
- Pediatric SRNVM, while rare, frequently stem from inflammatory or infectious causes.
- Spontaneous involution is a common outcome for untreated pediatric SRNVM, often leading to favorable visual acuity.
- The presence of a hyperpigmented ring on fluorescein angiography may serve as a predictive marker for spontaneous involution and a better visual prognosis in pediatric SRNVM.
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