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[Spontaneous brain abscess--bacteriology, therapy and prognosis]
1Universität Ulm, Klinik für Neurochirurgie, Günzburg.
Zentralblatt Fur Neurochirurgie
|January 1, 1995
Summary
Spontaneous intracranial abscesses, though rare, saw an increase in cases. Minimal invasive surgery and antibiotics offer a good prognosis, but delayed diagnosis or resistant bacteria increase mortality.
Area of Science:
- Neurosurgery
- Infectious Diseases
Context:
- Spontaneous intracranial abscesses are rare in Western countries, with neurosurgical centers typically seeing 2-4 cases annually.
- This study observed an increase in intracranial abscess cases treated at a single center.
- Potential causes included odontogenic, middle ear, and pulmonary infections, with some cases of unknown origin.
Purpose:
- To report on a recent increase in spontaneous intracranial abscesses.
- To analyze the origins, pathogens, and treatment outcomes of these abscesses.
- To evaluate the effectiveness of minimal invasive neurosurgical aspiration and antibiotic therapy.
Summary:
- Eight cases of spontaneous intracranial abscesses were treated over ten months, exceeding the expected annual rate.
- Streptococcus was the most common pathogen identified.
- Minimal invasive neurosurgical aspiration combined with long-term antibiotic therapy was the primary treatment approach.
Impact:
- Minimal invasive neurosurgical aspiration and antibiotic therapy demonstrate a good prognosis with low morbidity.
- Delayed diagnosis or highly resistant microorganisms significantly increase mortality rates.
- Further observations are warranted to understand the observed increase in cases.