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Related Experiment Videos

Expanding indications for permanent pacemakers

M Glikson1, R E Espinosa, D L Hayes

  • 1Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic, Rochester, MN 55905, USA.

Annals of Internal Medicine
|September 15, 1995
PubMed
Summary
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Permanent cardiac pacing shows promise for conditions like hypertrophic cardiomyopathy and long QT syndrome, offering symptom relief. Further research is needed to confirm its effectiveness in these expanding indications.

Area of Science:

  • Cardiology
  • Electrophysiology
  • Medical Devices

Background:

  • Permanent cardiac pacing is traditionally used for bradyarrhythmias.
  • Newer applications are emerging for various cardiac conditions.

Purpose of the Study:

  • To review clinical experience with new and expanding indications for permanent cardiac pacing.
  • To assess the efficacy of pacing in cardiomyopathies, arrhythmias, and syncope.

Main Methods:

  • A comprehensive literature search of MEDLINE (1980-1994) and manual searches were conducted.
  • Peer-reviewed articles and relevant abstracts on pacing indications were reviewed.
  • Data were extracted and summarized for specific conditions.

Main Results:

Related Experiment Videos

  • Pacing offers symptomatic and hemodynamic benefits in hypertrophic obstructive cardiomyopathy.
  • Pacing effectively reduced symptoms and syncope in long QT syndrome unresponsive to medical therapy.
  • Preliminary data suggest benefits in dilated cardiomyopathy and atrial fibrillation prevention; further studies are required.
  • Pacing in cardiac transplant recipients has improved; its role in vasovagal syncope requires further clarification.

Conclusions:

  • Pacing demonstrates promising effects for several newly recognized cardiac conditions.
  • Limited peer-reviewed clinical trials necessitate further research to validate these findings.
  • Improved patient selection and understanding of mechanisms are crucial for optimizing pacing therapy.