Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Cholesteatoma surgery: the individualized technique

S Karmarkar, S Bhatia, E Saleh

    The Annals of Otology, Rhinology, and Laryngology
    |August 1, 1995
    PubMed
    Summary

    Open cavity procedures for cholesteatoma surgery show significantly lower rates of residual or recurrent disease compared to closed procedures. Hearing outcomes were comparable between the two surgical approaches.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Phase II trial of 5-fluorouracil, leucovorin, interferon-alpha-2a, and cisplatin as neoadjuvant chemotherapy for locally advanced esophageal carcinoma.

    Cancer·1996
    Same author

    Intake of macronutrients and risk of breast cancer.

    Lancet (London, England)·1996
    Same author

    Increased circulating intercellular adhesion molecule-1 levels in type II diabetic patients: the possible role of metabolic control and oxidative stress.

    Metabolism: clinical and experimental·1996
    Same author

    Regional wall motion analysis by dobutamine stess echocardiography to distinguish between ischemic and nonischemic dilated cardiomyopathy.

    American heart journal·1996
    Same author

    Pleomorphic adenoma and adenoid-cystic carcinoma of salivary glands: immunohistochemical assessment of proliferative activity in comparison with flow-cytometric study.

    Cell proliferation·1996
    Same author

    The centromere as a target for the induction of chromosome damage in resting and proliferating mammalian cells: assessment of mitomycin C-induced genetic damage at kinetochores and centromeres by a micronucleus test in mouse splenocytes.

    Mutagenesis·1996

    Area of Science:

    • Otolaryngology
    • Surgical Pathology
    • Medical Research

    Background:

    • Cholesteatoma, a skin growth in the middle ear, requires surgical intervention.
    • Open and closed cavity techniques are common surgical approaches.
    • Individualizing surgical techniques is crucial for optimal patient outcomes.

    Purpose of the Study:

    • To compare residual/recurrent cholesteatoma rates between open and closed cavity procedures.
    • To evaluate hearing outcomes in patients undergoing open versus closed cavity surgery.
    • To determine the best indications for individualizing surgical approaches for cholesteatoma.

    Main Methods:

    • Retrospective analysis of 433 surgically treated cholesteatoma cases.
    • Data collected over a 7-year period at Gruppo Otologico, Piacenza, Italy.

    Related Experiment Videos

  • Comparison of residual/recurrent disease and hearing results between open and closed cavity procedures.

    • Main Results:

    • Open cavity procedures had lower residual cholesteatoma rates (10%) and recurrent cholesteatoma rates (2.38%) compared to closed procedures (31.22% and 11.16%, respectively).
    • Persistent otorrhea was rare, occurring in 1 open cavity case and 2 closed cavity cases.
    • Hearing results were slightly better in closed procedures but not statistically significant.

    Conclusions:

    • Open cavity procedures are associated with lower rates of residual and recurrent cholesteatoma.
    • Both techniques offer comparable hearing outcomes.
    • Surgical technique selection should consider the lower recurrence rates of open cavity procedures.