Multiple keratoacanthomata. A unique case and review of the current classification

A case of multiple keratoacanthomata is described, with involvement of the palms and soles, and erosive lesions of the eyelids and penis. Several lesions healed spontaneously, leaving circular scars. Some were atypical clinically, taking the form of keratotic tumors. Methotrexate produced marked improvement of all lesions but had to be abandoned because of thrombocytopenia. The current classification of keratoacanthomata is reviewed.