Related Experiment Video
Updated: Aug 11, 2026

Drug Treatment by Central Venous Catheter in a Mouse Model of Angiotensin II Induced Abdominal Aortic Aneurysm and Monitoring by 3D Ultrasound
Published on: August 4, 2022
Percutaneously inserted silastic jugular hemodialysis catheters seldom cause jugular vein thrombosis
M Agraharkar1, S Isaacson, D Mendelssohn
1Division of Nephrology, Wellesley Hospital, Toronto, Ontario, Canada.
Insights
Internal jugular vein cannulation for hemodialysis access showed a low incidence of thrombosis. Percutaneous insertion appears less damaging than surgical methods for vascular access in end-stage renal failure patients.
Area of Science:
- Nephrology
- Vascular Surgery
- Radiology
Background:
- Vascular access is crucial for hemodialysis in end-stage renal failure.
- Internal jugular vein cannulation is a common method for vascular access.
- Assessing the risk of jugular vein thrombosis is important for patient safety.
Purpose of the Study:
- To determine if internal jugular vein cannulation with soft silastic hemodialysis catheters causes jugular vein thrombosis.
- To compare the incidence of thrombosis between percutaneous and surgical cannulation methods.
Main Methods:
- Doppler ultrasound examinations were performed on 96 hemodialysis patients.
- 144 catheter insertion episodes in 116 internal jugular veins were evaluated.
- Thrombosis incidence was assessed for percutaneous and surgical Quinton PermCath insertions.
Main Results:
- Two cases of internal jugular vein thrombosis were identified in 101 veins with percutaneous insertions.
- Five cases of internal jugular vein thrombosis were found in 15 veins with surgical Quinton PermCath insertions.
- The incidence of thrombosis was acceptably low for percutaneous cannulation.
Conclusions:
- Percutaneous internal jugular vein cannulation for hemodialysis access results in a low incidence of jugular vein thrombosis.
- Internal jugular vein is a suitable option for vascular access in end-stage renal failure.
- Percutaneous cannulation is associated with less venous damage compared to surgical insertion.
Abstract:
To find out whether internal jugular vein cannulation with a soft silastic hemodialysis access catheter causes jugular vein thrombosis, the authors carried out Doppler ultrasound examinations on 96 patients receiving hemodialysis who had undergone 144 separate catheter insertion episodes in 116 veins. Two internal jugular vein thromboses were found in 101 veins that had been the site of percutaneous insertions only. In addition, 5 internal jugular vein thromboses were identified in 15 veins that had been cannulated surgically with the Quinton PermCath. The authors conclude that percutaneous internal jugular vein cannulation for hemodialysis access causes an acceptably low incidence of jugular vein damage. This strengthens the case for preferential use of the internal jugular vein for vascular access in patients with end-stage renal failure, and suggests that percutaneous cannulation is less damaging than surgical insertion.
Related Concept Videos
Extracorporeal Removal of Drugs: Peritoneal Dialysis and Hemodialysis
Venous Thrombosis III: Interprofessional Care
Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications
Hemodialysis I: Introduction
Hemodialysis II: Procedure and Complications
Hemodialysis III: Nursing Management

