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Related Experiment Videos

Flow in a rotating membrane plasma separator

R M Lueptow1, A Hajiloo

  • 1Department of Mechanical Engineering, Northwestern University, Evanston, IL 60208, USA.

ASAIO Journal (American Society for Artificial Internal Organs : 1992)
|April 1, 1995
PubMed
Summary
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Computational fluid dynamics reveals Taylor vortices in rotating filter separators, crucial for plasma separation. Vortex behavior changes downstream due to blood viscosity, impacting fluid transport efficiency.

Area of Science:

  • Biomedical Engineering
  • Fluid Dynamics
  • Medical Device Technology

Background:

  • Rotating filter separators efficiently separate plasma from whole blood.
  • Detailed understanding of the internal flow dynamics within these separators is lacking.
  • Investigating flow fields is essential for optimizing separator performance.

Purpose of the Study:

  • To computationally model and analyze the flow field within a commercial rotating filter separator.
  • To understand the formation, behavior, and impact of Taylor vortices on fluid transport.
  • To investigate the influence of blood viscosity changes on flow dynamics.

Main Methods:

  • Utilized the finite element code FIDAP for computational fluid dynamics (CFD) modeling.
  • Simulated the flow field within the annulus of a commercial rotating filter separator.

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  • Analyzed the emergence and disappearance of Taylor vortices and their effect on fluid transport.

    • Main Results:

    • Taylor vortices were observed at the upstream end of the annulus, diminishing downstream.
    • Increased blood viscosity, due to plasma removal, caused the disappearance of Taylor vortices.
    • Fluid transport is influenced by both vortex translation and fluid winding around vortices.
    • Reducing inertial effects of axial flow enhances vortex translation-driven transport.

    Conclusions:

    • Taylor vortices play a significant role in fluid transport within rotating filter separators.
    • Blood viscosity changes dynamically affect vortex behavior and fluid dynamics.
    • Optimizing flow fields by managing inertial effects can improve plasma separation efficiency.