Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Benefits and risks of fluoride supplements]

P Chavassieux1, P J Meunier

  • 1Inserm, unité 403, faculté Alexis-Carrel, Lyon, France.

Archives De Pediatrie : Organe Officiel De La Societe Francaise De Pediatrie
|June 1, 1995
PubMed
Summary

Fluoride is vital for strong teeth and bones, preventing cavities at low doses. However, excessive intake can lead to skeletal fluorosis, so avoid combining different fluoride supplements.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Pre-treatment bone turnover does not influence the level of the response to alendronate in postmenopausal osteoporosis at the bone tissue level.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2023
Same author

Ethical guidelines for publication of research.

Calcified tissue international·2016
Same author

Response to the Letter: Are Biochemical Markers of Bone Turnover Representative of Bone Histomorphometry in 370 Postmenopausal Women?

The Journal of clinical endocrinology and metabolism·2016
Same author

Chronic administration of Glucagon-like peptide-1 receptor agonists improves trabecular bone mass and architecture in ovariectomised mice.

Bone·2015
Same author

Excessive growth hormone expression in male GH transgenic mice adversely alters bone architecture and mechanical strength.

Endocrinology·2015
Same author

Bone safety with risedronate: histomorphometric studies at different dose levels and exposure.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2014

Area of Science:

  • Biochemistry
  • Mineral Metabolism
  • Public Health

Context:

  • Fluoride is an essential trace element integral to calcified tissues.
  • Its effects vary significantly based on dosage, influencing both dental and skeletal health.
  • Understanding these dose-dependent effects is crucial for public health recommendations.

Purpose:

  • To elucidate the dual role of fluoride in human health, acting as a prophylactic agent against dental caries and a therapeutic agent for osteoporosis.
  • To highlight the risks associated with high fluoride intake, including skeletal fluorosis and pseudorachitism in children.
  • To review various methods of fluoride supplementation for caries prevention in children.

Summary:

  • Low fluoride doses (<1.5 mg/day) promote dental caries prevention via enamel absorption.
  • Therapeutic doses (15-25 mg/day) are used for osteoporosis in adults.
  • High doses can cause skeletal fluorosis; excessive intake in children can lead to pseudorachitism.

Impact:

  • Informs optimal fluoride supplementation strategies for dental caries prevention in children.
  • Provides guidance on therapeutic uses of fluoride in adults for conditions like osteoporosis.
  • Emphasizes the critical need to prevent excessive fluoride intake by avoiding the combination of different supplement forms.

Related Experiment Videos