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Case report: brain metastases from papillary carcinoma thyroid

R Jyothirmayi1, J Edison, P P Nayar

  • 1Department of Radiotherapy and Clinical Oncology, Regional Cancer Centre, Trivandrum, India.

The British Journal of Radiology
|July 1, 1995
PubMed
Summary

Papillary thyroid cancer rarely spreads to the brain. This study presents two rare cases of brain metastasis from papillary thyroid cancer, highlighting this unusual clinical presentation.

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Area of Science:

  • Oncology
  • Neurology
  • Endocrinology

Background:

  • Papillary thyroid carcinoma is the most common type of thyroid cancer.
  • It generally has a favorable prognosis with a low rate of distant metastasis.
  • Brain metastasis from this cancer is exceptionally rare.

Observation:

  • This report details two patients with histologically confirmed brain metastases from papillary thyroid cancer.
  • One patient presented with a cerebellar hemisphere lesion.
  • The other patient had a frontal lobe metastasis.

Findings:

  • The incidence of brain metastasis from papillary thyroid cancer is estimated between 0.1% and 5%.
  • These cases represent unusual sites of metastasis within the brain.
  • Literature review supports the rarity of this condition.

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Implications:

  • Increased awareness of rare metastatic patterns in papillary thyroid cancer is crucial for timely diagnosis.
  • Understanding these rare presentations can aid in patient management and treatment strategies.
  • Further research into the mechanisms of brain metastasis in thyroid cancer is warranted.