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Related Experiment Videos

Bacteremia in conjunction with endodontic therapy

G J Debelian1, I Olsen, L Tronstad

  • 1Division of Endodontics, Department of Oral Biology, Faculty of Dentistry, University of Oslo, Norway.

Endodontics & Dental Traumatology
|June 1, 1995
PubMed
Summary

Oral bacteria can enter the bloodstream during root canal therapy. This study identified specific anaerobic microorganisms from root canals and bloodstream samples in patients undergoing endodontic treatment.

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Area of Science:

  • Endodontics
  • Oral Microbiology
  • Infectious Diseases

Background:

  • Asymptomatic apical periodontitis is a common dental condition.
  • Endodontic therapy aims to treat infected root canals.
  • Microbial dissemination from the root canal to the bloodstream is a potential concern.

Purpose of the Study:

  • To characterize oral microorganisms spreading from the root canal to the bloodstream during endodontic therapy.
  • To investigate the influence of instrumentation extent on microbial dissemination.
  • To identify the source of microorganisms found in the blood post-treatment.

Main Methods:

  • Aseptic microbiological sampling of root canals and blood from 26 patients.
  • Endodontic treatment with two different instrumentation depths (apical foramen vs. 1mm short).
  • Isolation and identification of anaerobic microorganisms using biochemical tests and antibiograms.

Main Results:

  • Anaerobic microorganisms were consistently isolated from all root canals.
  • Specific bacteria (e.g., Propionibacterium acnes, Prevotella intermedia) were detected in blood samples.
  • Identical microbial profiles in root canal and blood samples strongly suggested the root canal as the origin.

Conclusions:

  • Endodontic therapy can lead to the spread of oral microorganisms into the bloodstream.
  • The extent of root canal instrumentation may influence the types of microorganisms disseminated.
  • The root canal system is a likely source of bacteremia following endodontic procedures.

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