Related Experiment Video
Updated: Aug 15, 2026

Analysis of the Ambient Particulate Matter-induced Chromosomal Aberrations Using an In Vitro System
Published on: December 21, 2016
[Case-control studies to assess relative risk in proximity of putative sources of environmental pollution]
Abstract:
This paper discusses the analysis of the disease risk as function of distance from prespecified exposure sources. Instead of the usual ecological framework, the proposed model is based on individual data and includes the major individual risks factors as covariates. The risk due to environmental exposure is modelled using excess relative risk as effect measure, while the effect of individual risk factors is modelled using relative risk. A case-control design is proposed to fit this model and to obtain effect estimates.
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