Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Sclerotic fibroma]

M Wilk1, H W Kaiser, K H Steen

  • 1Hautklinik und Poliklinik, Rheinischen Friedrich-Wilhelms-Universität, Bonn.

Der Hautarzt; Zeitschrift Fur Dermatologie, Venerologie, Und Verwandte Gebiete
|June 1, 1995
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Prevalence and factors associated with professional burnout in Polish oncologists-results of a nationwide survey.

ESMO open·2024
Same author

Antagonist activation exercises elicit similar post-activation performance enhancement as agonist activities on throwing performance.

BMC sports science, medicine & rehabilitation·2023
Same author

Hydrothermal carbonization of the wet fraction from mixed municipal solid waste: Hydrochar characteristics and energy balance.

Waste management (New York, N.Y.)·2022
Same author

Modelling analysis and prediction of women javelin throw results in the years 1946 - 2013.

Biology of sport·2017
Same author

Tritium dynamics in soils and plants grown under three irrigation regimes at a tritium processing facility in Canada.

Journal of environmental radioactivity·2016
Same author

Levels of tritium in soils and vegetation near Canadian nuclear facilities releasing tritium to the atmosphere: implications for environmental models.

Journal of environmental radioactivity·2014

Sclerotic fibromas are benign skin tumors that can be misdiagnosed. This study details five cases, highlighting their distinct histology and effective surgical treatment, expanding knowledge on fibrous skin lesions.

Area of Science:

  • Dermatopathology
  • Sclerosing skin lesions
  • Tumor biology

Context:

  • Sclerotic fibroma diagnosis is crucial due to potential Cowden's syndrome association.
  • Histological features can lead to misdiagnosis despite distinctive appearance.
  • Understanding sclerotic fibroma is vital for accurate clinical and pathological assessment.

Purpose:

  • To present five cases of sclerotic fibroma.
  • To describe clinical and histological findings.
  • To discuss diagnostic challenges and treatment outcomes.

Summary:

  • Five cases (2 female, 3 male) of sclerotic fibroma located on the head, arm, and leg were analyzed.
  • Clinically, lesions presented as firm nodules (0.5-1.2 cm). Histologically, they showed storiform collagen bundles, vimentin-positive fibroblasts, and myofibroblasts expressing alpha-smooth-muscle actin.

Related Experiment Videos

  • Dermal dendritic cells (DD) expressing factor XIIIa were abundant, while CD34+ DD were sparse, mirroring normal skin distribution.

    • Impact:

    • Surgical excision appears curative for sclerotic fibroma.
    • This study expands the spectrum of fibrous lesions expressing alpha-smooth-muscle actin.
    • Accurate diagnosis of sclerotic fibroma improves patient management and avoids unnecessary concern for associated syndromes.