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Metastatic orbital tumors

I Günalp1, K Gündüz

  • 1Ocular Oncology Department, Faculty of Medicine, University of Ankara, Turkey.

Japanese Journal of Ophthalmology
|January 1, 1995
PubMed
Summary
This summary is machine-generated.

Orbital metastases are rare, with breast, neuroblastoma, and lung cancers being the most common primary tumors. Treatment outcomes varied, with some patients showing improvement after radiotherapy and chemotherapy.

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Area of Science:

  • Ophthalmology
  • Oncology

Background:

  • Metastatic orbital disease is an uncommon clinical presentation.
  • Understanding the primary sources and clinical course is crucial for patient management.

Purpose of the Study:

  • To review the clinical data of patients with metastatic orbital disease.
  • To identify common primary tumor types, presenting signs, and treatment outcomes.

Main Methods:

  • Retrospective review of clinical data from 28 patients diagnosed between 1972 and 1993.
  • Analysis of patient demographics, primary tumor types, orbital signs, and treatment responses.

Main Results:

  • Breast carcinoma (28.6%), neuroblastoma (25.0%), and lung carcinoma (21.4%) were the most frequent primary tumors.

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  • Proptosis, motility disturbance, and orbital mass were the most common presenting signs.
  • Treatment with radiotherapy and chemotherapy showed variable improvement in orbital signs and visual acuity.

    • Conclusions:

    • Metastatic orbital disease originates from various primary cancers, with breast, lung, and neuroblastoma being most prevalent.
    • Early recognition and multidisciplinary treatment approaches are essential for managing orbital metastases.
    • Prognosis varies significantly based on the primary tumor type and treatment response.