Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

A new sigmoidal function describing the small field dose profile data from a linear accelerator

C F Lam1

  • 1Department of Biometry and Epidemiology, Medical University of South Carolina, Charleston 29425, USA.

Medical Physics
|May 1, 1995
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Two-dimensional photonic-crystal vertical-cavity array for nonlinear optical image processing.

Applied optics·2008
Same author

The effects of inhalation of a novel nitric oxide donor, DETA/NO, in a patient with severe hypoxaemia due to acute respiratory distress syndrome.

Anaesthesia and intensive care·2002
Same author

Determination of optimal data placement for psychometric function estimation: a computer simulation.

The Journal of the Acoustical Society of America·1999
Same author

A systematic study of low-resolution recognition in protein--protein complexes.

Proceedings of the National Academy of Sciences of the United States of America·1999
Same author

C1 inhibitor removes the entire C1qr2s2 complex from anti-C1Q monoclonal antibodies with low binding affinities.

Immunology·1999
Same author

An efficient method for small field treatment dose calculation for stereotactic radiosurgery using a LINAC.

Medical physics·1998
Same journal

Correction to "On the shape of the radiation survival curve in tumor spheroids: The role of oxygen heterogeneity".

Medical physics·2026
Same journal

Multi-view constrained semi-supervised vertebra detection for 3D ultrasound spine volume.

Medical physics·2026
Same journal

Accuracy of quantitative <sup>177</sup>Lu SPECT/CT imaging: A systematic review.

Medical physics·2026
Same journal

Physics-constrained dual-domain network for CBCT reconstruction from orthogonal X-rays in gynecologic radiotherapy.

Medical physics·2026
Same journal

Decomposition-based harmonization for quantitative PET imaging across scanners and radiotracers.

Medical physics·2026
Same journal

Development and evaluation of an in vivo dose-based monitoring system for electron FLASH radiation therapy.

Medical physics·2026
See all related articles

A new sigmoidal function accurately models dose profiles for stereotactic radiosurgery. This method improves dose calculations for small circular fields, enhancing treatment planning precision.

Area of Science:

  • Medical Physics
  • Radiotherapy
  • Radiation Oncology

Background:

  • Dose profile data from small circular fields are crucial for stereotactic radiosurgery treatment planning.
  • Current methods typically use 2D interpolation of measured beam profiles from circular collimators.
  • Accurate dose calculation is essential for effective and safe radiation delivery.

Purpose of the Study:

  • To develop a novel method for describing dose profile data from small circular fields used in radiosurgery.
  • To introduce a new three-parameter sigmoidal function for fitting transformed dose profile data.
  • To provide an alternative to traditional interpolation methods for dose calculation.

Main Methods:

  • Transformed dose profile data into a sigmoidal form.

Related Experiment Videos

  • Developed and applied a new three-parameter sigmoidal function to fit the transformed data.
  • Analyzed the relationship between the function's parameters and axial depth, finding linear or exponential trends.
  • Main Results:

    • The new sigmoidal function effectively fits the transformed dose profile data.
    • The parameters of the sigmoidal function exhibit predictable relationships (linear or exponential) with axial depth.
    • This allows for the calculation of dose at any depth and radial distance.

    Conclusions:

    • The developed sigmoidal function offers a precise method for characterizing dose profiles from small circular fields.
    • This approach provides an alternative to linear interpolation, potentially improving dose calculation accuracy in stereotactic radiosurgery.
    • The findings contribute a new formula for describing dose distribution in small field radiotherapy.