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Related Experiment Videos

Pulmonary Gaucher's disease: high-resolution computed tomographic features

A Tunaci1, Y M Berkmen, E Gökmen

  • 1Department of Radiology, University of Istanbul, Istanbul School of Medicine, Turkey.

Pediatric Radiology
|January 1, 1995
PubMed
Summary

Pulmonary Gaucher's disease, a rare condition, shows specific patterns on CT scans. This study details the initial CT findings in a patient with biopsy-proven Gaucher's disease lung involvement.

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Area of Science:

  • Pulmonology
  • Radiology
  • Genetics

Background:

  • Gaucher's disease is a rare genetic disorder.
  • Pulmonary involvement in Gaucher's disease is uncommon and poorly described.
  • Previous imaging findings in pulmonary Gaucher's disease have not been reported.

Observation:

  • A patient with type I Gaucher's disease and lung involvement was studied.
  • Chest radiography revealed linear and reticulo-nodular opacities.
  • High-resolution computed tomography (HRCT) was utilized for detailed imaging.

Findings:

  • HRCT demonstrated thickening of the interlobular septa.
  • Multiple small nodules (4-6) were observed within secondary lobules.
  • These nodules likely represent individual acini affected by the disease.

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Implications:

  • This study provides the first report of CT findings in pulmonary Gaucher's disease.
  • Understanding these imaging patterns can aid in early diagnosis.
  • Further research is needed to confirm and expand upon these initial observations.