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Related Experiment Videos

Postnatal development of the central skull base: normal variants

L A Madeline1, A D Elster

  • 1Department of Radiology, Bowman Gray School of Medicine, Wake Forest University, Winston-Salem, NC 27157-1022, USA.

Radiology
|September 1, 1995
PubMed
Summary

This study identifies 16 normal skull base variants in children using computed tomography (CT) scans. Recognizing these common findings is crucial for diagnosing skull base developmental disorders.

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Area of Science:

  • Radiology
  • Pediatric Imaging
  • Skull Base Anatomy

Background:

  • The skull base is a complex region with intricate development.
  • Understanding normal variations is essential for accurate diagnosis of congenital anomalies.

Purpose of the Study:

  • To illustrate normal variants and developmental anomalies of the skull base.
  • To characterize normal developmental variants in the sphenoid and occipital bones on CT scans.

Main Methods:

  • Computed tomography (CT) scans of 189 children (0-18 years) without skull base deformity were analyzed.
  • Normal developmental variants in the sphenoid and occipital bones were identified and characterized.

Main Results:

  • Sixteen normal variants of central skull base development were identified.

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  • These variants include specific findings in the sphenoid and occipital bones, such as foramina, remnants, defects, clefts, and fusion variants.
  • Conclusions:

    • The identified variants correlate with the embryologic development of the skull base.
    • Recognizing these variants is necessary for evaluating pediatric skeletal dysplasias and skull base disorders.