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Rhythm disturbances after blood and crystalloid cardioplegia in coronary artery bypass grafting
E J Pehkonen1, P M Reinikainen, M J Kataja
1Department of Surgery, Tampere University Hospital, Finland.
Insights
Both blood and crystalloid cardioplegia increased postoperative rhythm disturbances in coronary artery bypass grafting patients. Myocardial ischemia, not the cardioplegia type, was linked to these arrhythmias.
Area of Science:
- Cardiology
- Cardiac Surgery
- Cardioplegia Research
Background:
- Coronary artery bypass grafting (CABG) requires myocardial protection.
- Cardioplegia solutions, including blood and crystalloid types, are used to achieve this.
- Postoperative arrhythmias are a known complication following cardiac surgery.
Purpose of the Study:
- To compare the incidence of postoperative rhythm disturbances between blood and crystalloid cardioplegia in CABG patients.
- To investigate the relationship between myocardial protection parameters and the occurrence of arrhythmias.
Main Methods:
- Randomized controlled trial involving 100 patients undergoing CABG.
- Patients received either blood or crystalloid cardioplegia.
- Holter monitoring was performed preoperatively and postoperatively in 83 patients.
Main Results:
- Both cardioplegia groups showed a significant increase in postoperative rhythm disturbances.
- No significant difference in arrhythmia occurrence was observed between blood and crystalloid cardioplegia groups.
- Arrhythmias were strongly associated with cross-clamp time, myocardial temperature, fibrillation time, CK-MB levels, and perioperative infarction.
Conclusions:
- The type of cardioplegia (blood vs. crystalloid) did not influence the incidence of immediate postoperative arrhythmias.
- Myocardial ischemia and inadequate myocardial protection are primary contributors to postoperative rhythm disturbances after CABG.
Abstract:
One hundred consecutive patients scheduled for coronary artery bypass grafting were randomized to receive either blood or crystalloid cardioplegia. Successful Holter monitoring for rhythm disturbances was done before and immediately after the operation in 83 cases. With both modes of cardioplegia there were increases in the occurrence of rhythm disturbances postoperatively. The increases were mostly statistically significant. There was no intergroup differences in the occurrence of arrhythmias. The association between these disturbances and cross-clamp times, myocardial temperatures during cross-clamping, myocardial fibrillation times during and after cross-clamping, CK-MB values and perioperative infarction all indicated ischaemia or incomplete myocardial protection as a major cause of the immediate postoperative rhythm disturbances.
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