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[The cell mediated immune response]

J S Haurum1

  • 1Institute of Molecular Medicine, John Radcliffe Hospital, Oxford, England.

Ugeskrift for Laeger
|July 3, 1995
PubMed
Summary

T-lymphocytes are key immune regulators. This review covers their function in immunity, infectious disease, cancer, and autoimmune disorders.

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Area of Science:

  • Immunology
  • Cellular Biology

Context:

  • T-lymphocytes are central to immune regulation and effector functions.
  • T-lymphocyte activation relies on recognizing peptide antigens via MHC molecules.
  • Different T-lymphocyte subsets (CD8+ cytotoxic, CD4+ T-helper) have distinct roles.

Purpose:

  • To review recent research on cell-mediated immune system functions.
  • To provide an overview of the immune system's role in health and disease.

Summary:

  • Recent findings on T-lymphocyte functions are presented.
  • The review details the T-lymphocyte mediated immune system's role in defense against pathogens and cancer.
  • It also explores its involvement in immune-mediated pathology and autoimmunity.

Impact:

  • Provides a comprehensive overview of T-lymphocyte roles in immunity.
  • Highlights the dual role of the cell-mediated immune system in protection and pathology.
  • Informs understanding of infectious diseases, cancer immunity, and autoimmune conditions.

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