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Perineural infiltration by cutaneous squamous cell carcinomas of the head and neck
C Di Gregorio1, V Gebbia, A M Florena
1Chair of Plastic Surgery, University of Palermo, Italy.
Anticancer Research
|May 1, 1995
Abstract:
In this paper six cases of cutaneous squamous cell carcinoma of the head and neck region with histologically-documented perineural tumoral infiltration are presented. Most patients showed recurrent disease during follow-up and have been treated with surgery and radiotherapy with or without systemic chemotherapy. The prognostic implications of perineural neoplastic infiltration as well as of therapeutic options are discussed.