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Do donor or recipient species influence calcification of bioprosthetic tissues?
S M Carpentier1, M H Monier, M Shen
1Laboratoire d'Etude des Greffes et Prothèses Cardiaques, Universitè de Paris, France.
The Annals of Thoracic Surgery
|August 1, 1995
Abstract:
To determine whether donor or recipient species influence calcification of bioprosthetic tissues, glutaraldehyde-treated valvar or pericardial specimens from different species (calf, sheep, pig) were subcutaneously implanted in different animals (rat, rabbit, cow, hen). Significant differences in the rate of calcification of the implanted specimens were found, which have important practical and theoretical implications for the development of valvular bioprostheses.