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Updated: Jul 25, 2026

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An Improved Mechanical Testing Method to Assess Bone-implant Anchorage
Published on: February 10, 2014
The effect of systemic flurbiprofen on bone supporting dental implants
M K Jeffcoat1, M S Reddy, I C Wang
1Department of Periodontics, University of Alabama School of Dentistry, Birmingham 35294, USA.
Journal of the American Dental Association (1939)
|March 1, 1995
Summary
Flurbiprofen, a non-steroidal anti-inflammatory drug, may help preserve bone density surrounding dental implants. This study suggests flurbiprofen, when used at correct dosages, can be effective in maintaining alveolar bone.
Area of Science:
- Dental Implantology
- Pharmacology
- Oral Surgery
Background:
- Alveolar bone loss is a common complication following dental implant placement.
- Maintaining sufficient bone volume is critical for long-term dental implant success.
- Non-steroidal anti-inflammatory drugs (NSAIDs) have demonstrated bone-modulating effects in various contexts.
Purpose of the Study:
- To evaluate the efficacy of flurbiprofen in preserving alveolar bone.
- To determine if flurbiprofen can mitigate bone loss around root-form dental implants in the mandible.
Main Methods:
- A study was conducted to assess flurbiprofen's impact on bone maintenance.
- The study focused on root-form dental implants placed in the mandible.
- Appropriate dosages of flurbiprofen were administered and monitored.
Main Results:
- Preliminary findings suggest flurbiprofen has a positive effect on bone preservation.
- The drug demonstrated potential in sparing alveolar bone around the implants.
- The efficacy was observed at specific, appropriate dosage levels.
Conclusions:
- Flurbiprofen shows promise as an adjunct therapy for maintaining alveolar bone around dental implants.
- Further research is warranted to confirm these preliminary findings and establish optimal treatment protocols.
- The use of flurbiprofen may contribute to improved outcomes in dental implantology.

