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Continuing experience with palliative chemical splanchnicectomy

D P Flanigan, R O Kraft

    Archives of Surgery (Chicago, Ill. : 1960)
    |April 1, 1978
    PubMed
    Summary
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    Open phenol splanchnicectomy effectively controls pain in patients with unresectable pancreatic cancer. This safe ancillary procedure offers significant pain relief and is recommended for advanced abdominal neoplasms.

    Area of Science:

    • Oncology
    • Surgical Gastroenterology
    • Pain Management

    Background:

    • Pancreatic carcinoma often presents with unresectable disease, leading to significant pain.
    • Effective pain management is crucial for improving the quality of life in patients with advanced abdominal neoplasms.

    Purpose of the Study:

    • To evaluate the efficacy and safety of open phenol splanchnicectomy for pain control in patients with unresectable pancreatic cancer.
    • To assess the impact of splanchnicectomy as an ancillary procedure during laparotomy.

    Main Methods:

    • Forty-one patients with unresectable pancreatic carcinoma underwent open phenol splanchnicectomy during initial laparotomy.
    • Twenty-three patients also received concomitant biliary and/or intestinal bypass procedures.

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    Main Results:

    • Operative mortality was 15%, with no deaths attributed to splanchnicectomy.
    • Eighty-eight percent of patients experienced postoperative pain relief.
    • Mean pain control duration was 4.3 months, with a mean survival of 5 months.

    Conclusions:

    • Open phenol splanchnicectomy is a safe and successful ancillary procedure for pain control in advanced intra-abdominal neoplasms.
    • It is recommended during initial laparotomy for patients with unresectable pancreatic cancer.