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Liver resection without blood transfusion

G Gozzetti1, A Mazziotti, G L Grazi

  • 1Second Department of Surgery, University of Bologna, Italy.

The British Journal of Surgery
|August 1, 1995
PubMed
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Blood transfusions after liver resections increase complications and impact long-term survival, especially in cirrhosis patients. Avoiding transfusions, where possible, improves patient outcomes and survival rates.

Area of Science:

  • Hepatobiliary Surgery
  • Transfusion Medicine
  • Surgical Oncology

Background:

  • Elective liver resections are complex procedures.
  • Blood transfusion practices in liver surgery have evolved.
  • Improved surgical techniques have reduced intraoperative blood loss.

Purpose of the Study:

  • To evaluate the impact of blood transfusion on immediate postoperative outcomes.
  • To assess the effect of blood transfusion on long-term survival after liver resection.
  • To identify factors influencing complications and survival in liver resection patients.

Main Methods:

  • Retrospective study of 522 elective liver resections.
  • Analysis of transfusion data and patient outcomes.
  • Stepwise logistic regression and multivariate analysis were employed.

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Main Results:

  • Transfusion was significantly associated with postoperative complications, particularly in patients with cirrhosis.
  • 59% of liver resections in the past 2 years did not require intraoperative transfusion.
  • Blood transfusion impacted long-term survival in patients with hepatocellular carcinoma and colorectal carcinoma metastases.

Conclusions:

  • Blood transfusion is a significant risk factor for postoperative complications and reduced survival after liver resection.
  • Careful transfusion strategies and improved surgical techniques are crucial for better patient outcomes.
  • Transfusion avoidance should be prioritized, especially in cirrhotic patients undergoing liver resection.