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Related Experiment Videos

Lobar hemorrhages in full-term neonates

W C Hanigan1, F C Powell, G Palagallo

  • 1Department of Neurosurgery, University of Illinois, College of Medicine at Peoria 61656, USA.

Child'S Nervous System : Chns : Official Journal of the International Society for Pediatric Neurosurgery
|May 1, 1995
PubMed
Summary

Neonatal lobar hemorrhage, often presenting with seizures, can occur without clear prenatal issues. Imaging like MRI helps assess brain injury, with most infants achieving developmental milestones without surgery.

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Area of Science:

  • Neonatal Neurology
  • Pediatric Radiology
  • Neurocritical Care

Background:

  • Neonatal lobar hemorrhage is a serious condition affecting newborns.
  • Understanding its causes and outcomes is crucial for clinical management.
  • Previous studies have explored risk factors and diagnostic methods.

Purpose of the Study:

  • To analyze cases of neonatal lobar hemorrhage over a five-year period.
  • To evaluate the diagnostic utility of computed tomography (CT) and magnetic resonance (MR) imaging.
  • To assess the clinical presentation, associated conditions, and neurodevelopmental outcomes.

Main Methods:

  • Retrospective chart analysis of four full-term neonates diagnosed with lobar hemorrhage.
  • Review of prenatal, obstetrical, and neonatal histories.

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  • Correlation of clinical presentation (seizures) with imaging findings (CT and MRI).

    • Main Results:

    • All four neonates presented with seizures within 48 hours of birth.
    • Perinatal asphyxia and isoimmune thrombocytopenia were identified in two cases.
    • CT was sufficient for diagnosis, while MRI provided detailed cortical injury and hemorrhage age assessment.
    • No surgical interventions were performed.
    • Three out of four children achieved developmental milestones at a mean follow-up of 3.3 years.

    Conclusions:

    • Neonatal lobar hemorrhage can occur in infants with uncomplicated perinatal histories.
    • Early diagnosis and detailed assessment of brain injury are facilitated by advanced imaging techniques.
    • Conservative management appears to yield favorable neurodevelopmental outcomes in a majority of cases.