Related Experiment Video
Updated: Oct 23, 2026

Mouse Kidney Transplantation: Models of Allograft Rejection
Published on: October 11, 2014
[Morphometry of the juxtaglomerular apparatus of allo-transplanted human kidneys]
Abstract:
Juxtaglomerular appartus of 17 allotransplanted human kidneys was studied by the karyometric method at various periods of existence in the recipient's organism. Kidneys of persons who died of craniocerebral trauma or acute cardiac incompetence served as control. At the early periods (up to 2 months) there was revealed an authentic increase in the nuclear volume of the epitheloid-modified cells of the afferent arteriole and of the Goormaghtigh cells. There was also a tendency to increase in the volume of the macula densa cells. At the late periods the juxtamolecular apparatus persisted in the allotransplanted kidneys with a but little injured parenchyma. Reduction of the juxtaglomerular appartus occurred in case of marked sclerosis and atrophy of the transplant parenchyma.
Related Concept Videos
Kidney Structure
Internal Anatomy of the Kidney
Anatomical Position and Dimensions
The kidneys are retroperitoneal organs positioned against the posterior abdominal wall on either side of the spine, roughly between the twelfth thoracic and third lumbar vertebrae. Each kidney is typically 10-12 cm long, 5-6 cm wide, and 3-4 cm thick, weighing about 150 grams.
Renal Cortex
The outermost region of the kidney is the...
Renal Tubule and Collecting Duct
Proximal Convoluted Tubule (PCT):
The PCT is the initial segment of the renal tubule, extending from the Bowman's capsule that encloses the glomerulus. Its convoluted structure and microvilli-lined cells increase the surface area for reabsorption. The PCT reabsorbs glucose, amino acids, sodium, and water from the filtrate, ensuring essential...
Anatomy of the Genitourinary System I: Kidneys and Ureters
Physiology of the Genitourinary System I: Renal Blood Flow and Glomerular Filtration

