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Systemic histiocytosis in the Bernese mountain dog
S Paterson1, P Boydell, R Pike
1Animal Medical Centre, Chorlton, Manchester.
The Journal of Small Animal Practice
|May 1, 1995
Summary
Systemic histiocytosis, a rare familial histiocytic disorder in Bernese mountain dogs, presents varied clinical signs. Some dogs achieve remission with treatment, while others require euthanasia.
Area of Science:
- Veterinary Medicine
- Canine Pathology
- Genetics
Background:
- Systemic histiocytosis is a rare, inherited histiocytic disorder predominantly affecting Bernese mountain dogs.
- Understanding its clinical presentation and progression is crucial for effective management.
Observation:
- This study details six confirmed cases of systemic histiocytosis in Bernese mountain dogs diagnosed between 1992 and 1994.
- The cases exhibited diverse clinical manifestations and disease trajectories.
Findings:
- Three dogs remain alive, with two achieving long-term remission (6 and 18 months post-diagnosis).
- One dog's owner declined treatment, and three dogs were humanely euthanized due to disease severity.
Implications:
- Early diagnosis and treatment may improve outcomes for Bernese mountain dogs with systemic histiocytosis.
- Further research into the genetic basis and therapeutic strategies for this disorder is warranted.
