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Orbital inflammatory syndrome: an unusual presentation
1Division of Ophthalmology, Mt Sinai Medical Center, Cleveland, Ohio, USA.
Summary
A rare orbital inflammatory syndrome presented as a well-circumscribed intraconal mass in a young woman. This case highlights the importance of histopathology in diagnosing orbital masses, differentiating from cavernous hemangioma.
Area of Science:
- Ophthalmology
- Pathology
- Neurosurgery
Background:
- Orbital masses can present with varied clinical signs, including unilateral proptosis.
- Cavernous hemangioma is a common benign orbital vascular tumor, typically located in the intraconal space.
- Accurate diagnosis of orbital masses is crucial for appropriate management and patient outcomes.
Observation:
- A 22-year-old woman presented with unilateral proptosis due to a large intraconal orbital mass.
- Initial imaging suggested a cavernous hemangioma.
- Surgical excision was performed via a lateral orbitotomy approach.
Findings:
- Histopathological examination revealed fibroblasts and inflammatory histiocytes.
- Electron microscopy confirmed the absence of cavernous hemangioma.
- The final diagnosis was orbital inflammatory syndrome, a rare entity presenting as a well-circumscribed intraconal mass.
Implications:
- This case represents the first documented instance of orbital inflammatory syndrome presenting as a well-circumscribed intraconal mass.
- It underscores the necessity of histopathological confirmation for orbital masses, even when imaging suggests a common diagnosis.
- The findings expand the differential diagnosis for intraconal orbital masses and inform surgical and diagnostic strategies.