Related Experiment Video
Updated: May 6, 2026

Percutaneous Hepatic Perfusion PHP with Melphalan as a Treatment for Unresectable Metastases Confined to the Liver
Published on: July 31, 2016
Pasteurella multocida peritonitis in hepatic cirrhosis with ascites
Abstract:
Two patients with spontaneous Pasteurella multocida peritonitis in association with cirrhosis and ascites are described. Both patients had close contact with domestic animals, but neither had been bitten. Both patients died, but only one as a result of his infection. We are aware of only one previous report of cirrhosis with spontaneous peritonitis caused by this organism. P. multocida should be considered as a possible cause of peritonitis in cirrhotic patients with a history of close contact with animals, particularly cats.
Insights
Pasteurella multocida peritonitis can occur spontaneously in cirrhosis patients with ascites and animal contact. This rare infection, often linked to cats, can be fatal, highlighting the need for clinical consideration.
Area of Science:
- Infectious Diseases
- Hepatology
Background:
- Cirrhosis and ascites create a vulnerable state for spontaneous bacterial peritonitis.
- Pasteurella multocida is a bacterium commonly found in domestic animals.
Observation:
- Two cases of spontaneous Pasteurella multocida peritonitis in patients with cirrhosis and ascites are presented.
- Both patients had significant contact with domestic animals, though no bites were reported.
- One patient died due to the infection, while the other succumbed to unrelated causes.
Findings:
- This study highlights a rare but serious association between Pasteurella multocida peritonitis and cirrhosis with ascites.
- The organism was identified as a cause of spontaneous peritonitis in cirrhotic patients with animal exposure.
- A previous report documented only one similar case, underscoring the rarity.
Implications:
- Pasteurella multocida should be considered in the differential diagnosis of peritonitis in cirrhotic patients, especially those with animal contact.
- Clinicians should inquire about animal exposure in cirrhotic patients presenting with peritonitis.
- Early recognition and treatment may be crucial for improving outcomes in these patients.
More Related Videos
Related Concept Videos
Pleural Effusion II: Symptoms and Management
A pleural effusion is the abnormal collection of fluid between the parietal and visceral pleura layers of tissue that form the lining of the lungs and chest cavity. It can occur independently or due to surrounding parenchymal diseases, such as infection, malignancy, or inflammatory conditions.
Clinical Manifestations:
Cirrhosis II: Pathophysiology
Portal Hypertension
Ascites
Hepatic Encephalopathy
Cholecystitis

