Related Experiment Video
Updated: May 6, 2026
09:02
Percutaneous Hepatic Perfusion PHP with Melphalan as a Treatment for Unresectable Metastases Confined to the Liver
Published on: July 31, 2016
11.4K
Pasteurella multocida peritonitis in hepatic cirrhosis with ascites
Gastroenterology
|March 1, 1976
Summary
Pasteurella multocida peritonitis can occur spontaneously in cirrhosis patients with ascites and animal contact. This rare infection, often linked to cats, can be fatal, highlighting the need for clinical consideration.
Area of Science:
- Infectious Diseases
- Hepatology
Background:
- Cirrhosis and ascites create a vulnerable state for spontaneous bacterial peritonitis.
- Pasteurella multocida is a bacterium commonly found in domestic animals.
Observation:
- Two cases of spontaneous Pasteurella multocida peritonitis in patients with cirrhosis and ascites are presented.
- Both patients had significant contact with domestic animals, though no bites were reported.
- One patient died due to the infection, while the other succumbed to unrelated causes.
Findings:
- This study highlights a rare but serious association between Pasteurella multocida peritonitis and cirrhosis with ascites.
- The organism was identified as a cause of spontaneous peritonitis in cirrhotic patients with animal exposure.
- A previous report documented only one similar case, underscoring the rarity.
Implications:
- Pasteurella multocida should be considered in the differential diagnosis of peritonitis in cirrhotic patients, especially those with animal contact.
- Clinicians should inquire about animal exposure in cirrhotic patients presenting with peritonitis.
- Early recognition and treatment may be crucial for improving outcomes in these patients.
More Related Videos
Related Concept Videos
01:28Pleural Effusion II: Symptoms and Management
1.4K
Pleural Effusion Overview
A pleural effusion is the abnormal collection of fluid between the parietal and visceral pleura layers of tissue that form the lining of the lungs and chest cavity. It can occur independently or due to surrounding parenchymal diseases, such as infection, malignancy, or inflammatory conditions.
Clinical Manifestations:
A pleural effusion is the abnormal collection of fluid between the parietal and visceral pleura layers of tissue that form the lining of the lungs and chest cavity. It can occur independently or due to surrounding parenchymal diseases, such as infection, malignancy, or inflammatory conditions.
Clinical Manifestations:
1.4K
01:24Cirrhosis II: Pathophysiology
53
Cirrhosis is a progressive chronic liver injury caused by prolonged inflammation, excessive fibrotic remodeling, and impaired regeneration. Over time, repeated hepatic insults disrupt the liver’s architecture and function, leading to reduced blood flow, impaired bile drainage, and diminished metabolic capacity.Pathophysiology of cirrhosisCirrhosis arises from three main responses to chronic liver damage: inflammation, immune activation, and hepatocyte death. These processes lead to...
53
01:22Portal Hypertension
58
Portal hypertension is an increase in blood pressure within the portal venous system. Normally, this pressure is less than 5 mmHg. It is considered clinically significant when it rises above 10 mmHg. At this threshold, complications from altered blood flow and venous congestion emerge.EtiologyPortal hypertension arises from conditions that impede blood flow through the liver. The most common cause is cirrhosis, in which chronic liver injury leads to fibrotic scarring. This fibrosis narrows or...
58
01:19Ascites
54
DefinitionAscites is the buildup of fluid inside the peritoneal cavity. It occurs when fluid moves out of the vascular system faster than the peritoneal lymphatics can remove it. This fluid shift is most commonly seen in liver cirrhosis but can also appear in several other systemic disorders.EtiologyCirrhosis remains the leading cause of ascites. Other conditions that can contribute include:Heart failureConstrictive pericarditisAbdominal cancersNephrotic syndromeSevere protein–calorie...
54
01:29Hepatic Encephalopathy
71
DefinitionHepatic encephalopathy is a reversible neurologic syndrome that results from advanced liver dysfunction or portosystemic shunting. It leads to disturbances in cognition, behavior, and motor function due to the brain’s exposure to gut-derived toxins that the liver fails to detoxify.EtiologyThis condition develops either in the setting of acute fulminant hepatitis or progressively during chronic liver disease, such as cirrhosis and portal hypertension. Portosystemic...
71
01:20Cholecystitis
33
Cholecystitis is inflammation of the gallbladder, most commonly caused by obstruction of the cystic duct. This blockage prevents bile from draining, leading to gallbladder distension, inflammation, and potentially serious complications. This condition may present acutely or chronically and can happen with or without gallstones.EtiologyAbout 95% of cholecystitis cases are calculous, caused by gallstones blocking the cystic duct, leading to bile accumulation and inflammation of the gallbladder...
33