Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

A translating-bed technique for total-body irradiation

L H Gerig1, J Szanto, T Bichay

  • 1Ottawa Regional Cancer Centre, Ontario, Canada.

Physics in Medicine and Biology
|January 1, 1994
PubMed
Summary

A new total-body irradiation (TBI) technique simplifies bone-marrow transplant preparation. This method uses a computer-controlled couch and PMMA spoilers, reducing treatment time and improving patient tolerance.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Pre-operative versus post-operative radiosurgery for brain metastasis: Effects on treatment volume and inter-observer variability.

Journal of radiosurgery and SBRT·2018
Same author

Sci-Thur AM: Planning - 10: Improved dosimetric accuracy for patient specific quality assurance using a dual-detector measurement method for cyberknife output factors.

Medical physics·2017
Same author

SU-E-T-173: TomoTherapy Treatment Couch Velocity Verification Using TomoDose.

Medical physics·2017
Same author

[Advanced directives in psychiatry: A review of the qualitative literature, a state-of-the-art and viewpoints].

L'Encephale·2013
Same author

A technique of heart puncture in the chicken for obtaining blood.

Journal of the American Veterinary Medical Association·2010
Same author

A septicemia with Klebsiella friedländeri in mink.

Canadian journal of comparative medicine and veterinary science·2010

Area of Science:

  • Radiation Oncology
  • Medical Physics

Background:

  • Total-body irradiation (TBI) is increasingly used with chemotherapy for bone-marrow transplantation.
  • Conventional dosimetry functions are inadequate for dynamic TBI delivery.

Purpose of the Study:

  • To describe a novel, simplified TBI technique for bone-marrow transplant patients.
  • To develop and validate dynamic dosimetry functions for this TBI method.

Main Methods:

  • Patients treated on a mobile couch with computer-controlled speed at 195 cm SSD.
  • Development of dynamic tissue maximum ratio (TMR) and percentage depth dose (PDD) functions.
  • Measurements in an anthropomorphic water phantom, including evaluation of polymethyl methacrylate (PMMA) beam spoilers.

Main Results:

Related Experiment Videos

  • The dynamic TBI technique is rapid (approx. 10 min per field) and well-tolerated.
  • Developed dynamic TMR and PDD functions accurately describe dose distribution.
  • 2.4 cm PMMA spoilers effectively provide full skin dose, eliminating the need for lateral bolus.

Conclusions:

  • The described dynamic TBI technique is effective, efficient, and safe for bone-marrow transplant preparation.
  • The use of PMMA spoilers simplifies the procedure and ensures adequate skin dose.
  • This method has been successfully applied to 55 patients since 1991.