The genetic effects of elevated temperature in the yeast, Saccharomyces cerevisiae

The growth of yeast cultures at supra-optimal temperatures up to 39 degrees C and exposure in non-nutrient solution up to 52 degrees C has been examined for the induction of genetic change. Both sets of conditions lead to the induction of mutation to antibiotic resistance, mitotic gene conversion, crossing-over and mitotic chromosomal non-disjunction.