Related Experiment Videos
Intraluminal lipids modulate avian gastrointestinal motility
V Martínez1, M Jiménez, E Gońalons
1Department of Cell Biology and Physiology, Veterinary Faculty, Universitat Autònoma de Barcelona, Spain.
The American Journal of Physiology
|August 1, 1995
Summary
Lipid infusion into the chicken gut alters gastrointestinal electrical activity. This suggests an "ileal brake" mechanism, similar to mammals, may slow digestion.
Area of Science:
- Gastroenterology
- Animal Physiology
- Digestive System Motility
Background:
- Intraluminal lipid infusion is known to affect gastric emptying and intestinal transit in certain species.
- Understanding lipid's impact on avian gastrointestinal electrical activity is crucial for comparative physiology.
Purpose of the Study:
- To investigate the effects of intraluminal lipid infusion on the gastrointestinal electrical activity in chickens.
- To characterize the specific actions of oleic acid and triolein on digestive motility.
Main Methods:
- Electromyography was used to record electrical activity in the stomach, duodenum, and small intestine of chickens.
- Chronic catheters were placed in the esophagus and ileum for infusing oleic acid (OA) or triolein (TO).
Main Results:
- Esophageal and ileal infusion of lipids (OA and TO) inhibited gastroduodenal cycle frequency.
- Ileal oleic acid infusion, along with esophageal infusions, increased antiperistaltic duodenal activity.
- Oleic acid administration prolonged the migrating myoelectric complex (MMC) duration and slowed phase III propagation.
Conclusions:
- Intraluminal lipid infusion modulates avian gastrointestinal motility.
- Observed effects include decreased gastric cycle frequency, increased duodenogastric reflux, and prolonged MMC.
- Findings suggest an "ileal brake" mechanism in chickens, analogous to that in mammals, potentially delaying gastric emptying.