Related Experiment Videos
[State of the blood circulation system in acute poisoning in young children]
Anesteziologiia I Reanimatologiia
|May 1, 1995
Insights
Cardiovascular issues are common in children with acute poisoning. Specific poisonings like clopheline and barbiturates cause distinct changes in heart function and blood flow.
Area of Science:
- Pediatric Toxicology
- Cardiovascular Medicine
- Clinical Pharmacology
Background:
- Cardiovascular involvement is a frequent complication during the acute toxicogenic phase of poisoning in children.
- Understanding poison-specific cardiovascular effects is crucial for effective management.
Purpose of the Study:
- To analyze cardiac function changes in infants experiencing acute poisonings.
- To identify characteristic cardiovascular and hemodynamic alterations associated with specific toxins.
Main Methods:
- Comprehensive examination of cardiac function in 168 infants.
- Analysis included electrocardiogram (ECG) and central/peripheral hemodynamic assessments.
- Infants were poisoned with clopheline, caustic poisons, barbiturates, and amitriptyline.
Main Results:
- Distinct changes in ECG parameters were observed across different poisoning types.
- Characteristic alterations in central and peripheral hemodynamics were identified for each poison.
- The findings highlight poison-specific cardiovascular profiles in pediatric poisoning.
Conclusions:
- Acute poisonings in children frequently manifest with cardiovascular involvement.
- Specific toxins induce unique and identifiable changes in cardiac function and hemodynamics.
- This study provides a basis for targeted cardiovascular assessment in pediatric poisoning cases.
Abstract:
The syndrome of cardiovascular involvement is one of the most frequently occurring syndromes in the toxicogenic phase of acute poisonings in children. Analysis of the results of comprehensive examination of cardiac function in 168 infants poisoned with clopheline, caustic poisons, barbiturates, and amitriptyline showed changes in the ECG and central and peripheral hemodynamics which are characteristic of each type of poisonings.