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Current indications for isotretinoin as a treatment for acne vulgaris
V Goulden1, A M Layton, W J Cunliffe
1Dermatology Department, General Infirmary at Leeds, UK.
Background:
There is at present little published information on the current indications for isotretinoin as a treatment of acne vulgaris.
Objectives:
To investigate the factors which influence our current prescribing of isotretinoin: acne severity, response to previous therapy, scarring and psychological effect.
Methods:
Data on the factors influencing treatment of 200 patients with isotretinoin between January 1993 and May 1994 were examined.
Results:
41% of patients were prescribed isotretinoin for partial response to previous therapy, 26% for partial therapy and scarring and 17% for partial response to treatment and psychological disturbance. Only 16 patients received isotretinoin for severe acne.
Conclusion:
Patients who show only partial response to conventional antibiotic therapy should be prescribed isotretinoin in order to minimize scarring and significant psychological disturbance, independently of the severity of the acne.
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