Related Experiment Videos
Raynaud's phenomenon in systemic lupus erythematosus
L T Lavras Costallat1, A M Valente Coimbra
1Department of Internal Medicine, State University of Campinas, Sao Paulo, Brazil.
Revue Du Rhumatisme (English Ed.)
|May 1, 1995
Summary
Raynaud
Area of Science:
- Rheumatology
- Clinical Medicine
Background:
- Systemic lupus erythematosus (SLE) is a chronic autoimmune disease.
- Raynaud's phenomenon (RP) is a common vascular complication in SLE patients.
Purpose of the Study:
- To investigate the clinical features and prevalence of Raynaud's phenomenon in Brazilian patients with systemic lupus erythematosus.
- To compare clinical manifestations between SLE patients with and without Raynaud's phenomenon.
Main Methods:
- Retrospective analysis of 123 SLE patients with RP and 149 SLE patients without RP.
- Data collected included demographics, disease onset and duration, clinical symptoms, and laboratory findings.
Main Results:
- SLE patients with RP showed a higher incidence of skin lesions, myalgia, and myopathy.
- These patients had a lower likelihood of developing nephritis and nephrotic syndrome.
- Pulmonary hypertension was exclusively observed in SLE patients with RP.
Conclusions:
- Raynaud's phenomenon is a frequent condition among Brazilian SLE patients.
- The presence of RP in SLE generally indicates a favorable prognosis, unless complicated by pulmonary hypertension.