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Current concepts of anticoagulation therapy

R D Hull1, G F Pineo

  • 1Department of Medicine, University of Calgary, Alberta, Canada.

Clinics in Chest Medicine
|June 1, 1995
PubMed
Summary

Clinical trials have advanced heparin and warfarin treatments for venous thromboembolism. Current research explores optimal oral anticoagulant duration and low-molecular-weight heparin

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Pooled analysis of trials may, in the presence of heterogeneity inadvertently lead to fragile conclusions due to the importance of clinically relevant variables being either hidden or lost when the findings are pooled.

Thrombosis research·2010

Area of Science:

  • Cardiology
  • Hematology
  • Clinical Trials

Background:

  • Heparin and warfarin have transformed venous thromboembolism (VTE) treatment.
  • Decade-long clinical trials have significantly impacted VTE management strategies.

Purpose of the Study:

  • To address unresolved questions in VTE treatment.
  • To discuss ongoing clinical trials investigating VTE therapies.

Main Methods:

  • Review of recent clinical trial findings.
  • Discussion of current research in VTE management.

Main Results:

  • Clinical trials have revolutionized VTE treatment approaches.
  • Ongoing trials focus on critical aspects of anticoagulant therapy.

Conclusions:

  • Further research is needed to optimize VTE treatment duration.
  • The role of low-molecular-weight heparin in VTE requires continued investigation.

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