[Results of hepatic resection for 600 cases with primary liver cancer]

Hepatic resection had been performed in 600 cases with primary liver cancer (PLC) in our hospital from 1964 to 1993. Among them, 24 cases underwent second hepatic resection because of tumor reccurrence. The ratio of male to female was 8.0:1. Most of the patients were 40 to 59 years old. and the age ranged from 8 to 78 years old. The positive rate of AFP was 57.4% (> 400 micrograms/L). of them, 84.4% were associated with hepatic cirrhosis. Hepatocellular carcinoma was verified in 91.6% of these cases. Small tumor (< 5cm in diameter) was found in 130 cases (21.7%). In this series, 10 cases underwent semi-hepatectomy and 590 cases underwent irregular hepatectomy. Spontaneous rupture of tumor was found in 29 cases. In 13 of 600 cases, hepatectomy was done after transcatheter hepatic arterial chemoembolization. Six of 600 cases underwent second stage hepatectomy because the tumots could not be resected during laparotomy. After multimodality therapy, including tumor ethanol injection treatment, microwave tumor coagulation and hepatic artery chemoembolization, the tumors became small and subsequently resected. In these 600 cases, 24 cases died within one month after hepatectomy with a mortality of 4.0%. The most common cause of death was hepatic failure. The 1-,3-,5-, 10-year survival rates were 61.9%, 40.2%, 33.0%, 29.2%, respectively in the whole series and 87.8%, 69.4%, 54.0%, 43.0% respectively in patients with small tumor.