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Follow-up of 30 pregnancies after embryo cryopreservation
I Heijnsbroek1, F M Helmerhorst, A F van den Berg-Helder
1Department of Obstetrics, Gynecology and Reproductive Medicine, Leiden University Hospital, The Netherlands.
Objective:
In an observational follow-up study, the pregnancy outcome of the first 30 women who conceived after transfer of cryopreserved embryos was evaluated.
Study Design:
The main outcome measures were duration and complications of pregnancy, mode of delivery, complications during and after childbirth, birthweight, Apgar score, and congenital anomalies.
Results:
Twenty-six pregnancies ended in birth of one (n = 22) or more (n = 4) infants with a cesarean section rate of 23%. Of the singleton pregnancies 77% were uncomplicated, but there was a high incidence of breech presentation (14%). Infant birthweight tended to be above average with 45% of singletons weighing more than the 75th centile of weight for gestation. There were no major congenital deformations.
Conclusion:
The results of our embryo cryopreservation program are encouraging, but sustained follow-up of such pregnancies and infants is needed.