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Related Experiment Videos

Excisional breast biopsy: when, why and how?

R Bellantone1, S Rossi, C P Lombardi

  • 1Institute of Clinical Surgery, Università Cattolica del Sacro Cuore, Rome, Italy.

International Surgery
|January 1, 1995
PubMed
Summary
This summary is machine-generated.

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Breast biopsy for palpable lumps with low cancer suspicion is safe and cost-effective under local anesthesia. Non-palpable lesions require careful evaluation to avoid unnecessary biopsies and associated costs.

Area of Science:

  • Oncology
  • Surgical Pathology
  • Radiology

Background:

  • Accurate preoperative diagnosis is crucial for determining appropriate breast biopsy anesthesia and patient management.
  • Palpable breast lumps and non-palpable mammographic findings present distinct diagnostic challenges.

Purpose of the Study:

  • To evaluate the safety and cost-effectiveness of local versus general anesthesia for palpable breast lump biopsies.
  • To assess the diagnostic yield and cost-benefit of biopsies for non-palpable mammographic lesions.

Main Methods:

  • Retrospective analysis of 673 patients undergoing excisional biopsy for palpable breast lumps, categorized by anesthesia type (local vs. general).
  • Analysis of 60 patients with non-palpable lesions detected by mammography undergoing biopsy.
  • Comparison of preoperative diagnostic accuracy, cancer detection rates, and cost implications.

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Main Results:

  • Local anesthesia for palpable lumps with low suspicion yielded high diagnostic accuracy (96.2% benign, 98.1% malignant).
  • Biopsies for non-palpable lesions revealed a 35% cancer rate, highest in stellate opacities (45%) and suspicious microcalcifications (50%).
  • No cancers were found in low-density masses or non-suspicious calcifications, suggesting unnecessary biopsies.

Conclusions:

  • Local anesthesia is a safe, economical, and preferred method for palpable breast lump biopsies when malignancy is not highly suspected.
  • Biopsies for non-palpable mammographic lesions should be selectively performed based on suspicious imaging features to optimize cost-effectiveness.